• Business Insider is coming to San Francisco on April 14.
• Our live event, The Long Play, will feature leaders who are shaping AI's impact across industries.
• If you have a question for our speakers, we want to hear it!

Longevity influencer Bryan Johnson, founder of Immortals, and horror movie producer Jason Blum, founder and CEO of Blumhouse, run very different businesses.

But both are prime examples of leaders who are rethinking strategies and refocusing careers as AI brings wave after wave of change to their industries.

And both will be on stage, interviewed by Business Insider journalists, at BI's first flagship event in San Francisco on April 14.

We know from our reporting that navigating the changes tied to AI and the industry shifts it's driving isn't easy. The Long Play is a chance to explore what it takes to adapt and build for what's ahead, learning from executives who are leading the charge.

Also on stage that evening: Joanna Strober, founder and CEO of Midi Health, and Carina Hong, founder and CEO of Axiom AI.

Strober, who has built a career as a two-time founder and venture capitalist, has a track record of spotting opportunities in overlooked markets, rallying investor enthusiasm to launch durable companies.

Hong is out to transform AI itself, arguing that the path to superintelligence runs through advanced mathematics. She's attracted major Silicon Valley talent to her young startup, which is already valued at $1.6B.

What do you want to hear from these leaders? Do you have a question you want them to answer? Drop it below for our reporters!

If you're in San Francisco, we still have a few seats left to join this conversation in person. Apply to attend here.

You can check out the full agenda for Business Insider's The Long Play, below. And keep an eye out for highlights and insights from the event.

What to expect at The Long Play, San Francisco

Betting Big on Superintelligence

AI is transformative. Too often, it's also wrong. Carina Hong is out to fix that problem with her startup, Axiom Math. In conversation with Senior Correspondent Ben Bergman, Hong will explain why advanced mathematics is key to superintelligence, how she has attracted top talent from across Silicon Valley, and where her company - already valued at $1.6B - goes next.

How Hollywood Can Survive in the AI Age

Disruption may be hitting Hollywood hard, but it's not slowing down Jason Blum whose powerhouse studio, Blumhouse, is behind many of the most popular - and most profitable - horror films of the past ten years. He joins Chief Correspondent Peter Kafka to unpack how AI has changed the entertainment industry and how his unique approach to business is setting Blumhouse up to thrive in a time of shifting consumer behaviors.

The Playbook for Spotting Opportunity

Joanna Strober, founder and CEO of Midi Health, knew there was a business opportunity in women's health, but it took grit and patience to help investors see it too. What started as a mission to provide digital care for women in middle age has quickly scaled into a unicorn company with big growth ambitions. A former lawyer, long-time VC and repeat founder, Strober speaks with editor in chief Jamie Heller about finding opportunity in overlooked markets.

Living Your Best Eternal Life?

Biohacker Bryan Johnson believes we will be "the first generation who won't die." He has spent millions in the quest for longevity, founding various companies along the way including his most recent, Immortals. In a wide-ranging conversation with Executive Editor Zak Jason, Johnson will talk about how AI is impacting our efforts to halt aging and increasing our need to focus on living in the present, what he's learned in his journey from tech entrepreneur to longevity influencer, and how all of us can optimize our lives for top performance.